Hotel MainStay Suites Texas Medical Center/Reliant Park

From 610: Take Fannin North exit, right(east)on Old Spanish Trail for 1 mile. Hotel on the right. From Bush Intercontinental Airport: Take Will Clayton Parkway to Highway 59 South to exit 288 South to exit Holcomb/Old Spanish Trail, go through light(Holcomb)and take a right at next street (Old Spanish Trail). Hotel on the left. From Hobby Airport: Take 45 North to exit 610 West to exit 288 North, to Old Spaish Trail exit. Hotel on the left. ## From 610: Take Fannin North exit, right(east)on Old Spanish Trail for 1 mile. Hotel on the right. From Bush Intercontinental Airport: Take Will Clayton Parkway to Highway 59 South to exit 288 South to exit Holcomb/Old Spanish Trail, go through light(Holcomb)and take a right at next street (Old Spanish Trail). Hotel on the left. From Hobby Airport: Take 45 North to exit 610 West to exit 288 North, to Old Spanish Trail exit. Hotel on the left.